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レドックスイメージンググループ研究業績

  • Eto H, Hyodo F*, Nakano K, Utsumi H. Selective imaging of malignant ascites in a mouse model of peritoneal metastasis using in vivo dynamic nuclear polarization (DNP)-MRI Analytical Chemistry 16;88(4):2021-7 2016
  • Ito S and Hyodo F, Dynamic nuclear polarization-magnetic resonance imaging at low ESR irradiation frequency for ascorbyl free radicals Scientific Reports 19;6:21407 2016
  • Kagiya G, Ogawa R, Hyodo F, Yamashita K, Nakamura M, Ishii A, Sejimo Y, Tominaga S,  Murata M, Tanaka Y, Hatashita M, Development of a real-time imaging system for hypoxic cell apoptosis   Molecular Therapy – Methods and Clinical Development 2016 in press
  • 兵藤文紀, 伊藤慎治, 内海英雄. 生体内分子・医薬品を用いた新たな代謝イメージング法の開発 薬学雑誌. 2016 in press

  • 園田紀之, 兵藤文紀, 大和真由実, 井口 登與志. 糖尿病モデル動物を用いたレドックスイメージングと病態との関連 薬学雑誌 2016 in press

  • Eto H, Hyodo F*, Kosem N, Kobayashi R, Yasukawa K, Nakao M, Kiniwa M, Utsumi H Redox imaging of skeletal muscle using in vivo DNP-MRI and its application to an animal model of local inflammation  Free Radical Biology and Medicine 23;89:1097-1104 2015

  • Utsumi H, Hyodo F. Free Radical Imaging using in vivo Dynamic Nuclear Polarization – MRI Methods in Enzymology 2015 35(5):739-43 2015

  • Benial AM, Dhas MK, Ichikawa K, Yamada K, Hyodo F, Jawahar A, Utsumi H. Diffusion studies of redox-sensitive nitroxyl spin probes through bilayer lipid membranes using 300 MHz electron spin resonance spectrometer. Biofizika. 60(1) 88-94 2015
  • 兵藤文紀, 伊藤慎治, 内海英雄. ReMIによる新たなレドックス分子イメージング法の開発と応用 薬学雑誌 135(5) 725-31 2015
  • 安西和紀, 兵藤文紀. Imaging in vivo redox metabolism. Yakugaku Zasshi. 15 135(5) 717-8. 2015
  • 加藤隆弘, 兵藤文紀, 大和真由実, 内海英雄, 神庭重信. 統合失調症とレドックスーReMIの統合失調症モデルへの応用― 薬学雑誌 135(5) 739-43 2015
  • 兵藤文紀、伊藤慎治 内海英雄 磁気共鳴法による生体酸化還元反応の可視化 分析化学 Vol.63 No, 6 p437-476 2014

  • Hyodo F, Ito S, Yasukawa K, Kobayashi R, Utsumi H. Simultaneous and spectroscopic redox molecular imaging of multiple free radical intermediates using dynamic nuclear polarization-magnetic resonance imaging. Analytical Chemistry 5 86(15) 7234-8 2014
  • Dhas KM, Utsumi H, Ichikawa K, Yamada K, Hyodo F, Benial M Diffusion Studies of Redox-Sensitive Nitroxyl Spin Probes through Bilayer Lipid Membranes using 300 MHz Electron Spin Resonance Spectrometer European Journal of Academic Essays 1(3) 70-75 2014
  • Benial M, Dhas K, Ichikawa K, Yamada KI, Hyodo F, Jawahar A Utsumi H: Permeability Studies of Redox-Sensitive Nitroxyl Spin Probes Through Lipid Membranes Using an L-Band ESR Spectrometer Applied Magnetic Resonance 44(4) 439-447 2013
  • Hyodo F, Davis RM, Hyodo E, Matsumoto S, Krishna MC, Mitchell JB. The relationship between tissue oxygenation and redox status using magnetic resonance imaging International Journal of Oncology. 41(6) 2103-2108 2012
  • Kosem N, Naganuma T, Ichikawa K, Phumala Morales N, Yasukawa K, Hyodo F, Yamada KI, Utsumi H. Whole-body kinetic image of a redox probe in mice using Overhauser-enhanced MRI.  Free Radical Biology and Medicine. 53(2) 328-36 2012
  • Matsumoto A, Matsumoto K, Matsumoto S, Hyodo F, Sowers AL, Koscielniak JW, Devasahayam N, Subramanian S, Mitchell JB, Krishna MC. intracellular hypoxia of tumor tissue estimated by noninvasive electron paramagnetic resonance oximetry technique using paramagnetic probes. Biological & Pharmaceutical Bulletin. 34(1) 142-5. 2011
  • Matsumoto K, Hyodo F, Anzai K, Utsumi H, Mitchell JB, Krishna MC. Brain redox imaging. Methods in Molecular Biology. 711 397-419 2011
  • 兵藤文紀、内海英雄 オーバーハウザーMRIを用いた生体レドックス疾患の可視化 人工血液   Vol.19 No, 1 p25-32 2011
  • Citrin D,Cotrim AP, Hyodo F, Baum BJ, Krishna MC and Mitchell JB. Radioprotectors and Mitigators of Radiation-Induced Normal Tissue Injury.; Oncologist 15(4) 360-71 2010
  • Miura D, Fujimura, Y, Yamato M, Hyodo F, Utsumi H, Tachibana H, Wariishi H. Ultra-highly sensitive in sistu metabolomic imaging for visualizing spatiotemporal metabolic behaviors. Analytical Chemistry 82(23) 9789-96 2010 C= 59回 IF=5.9
  • Samuni Y, Ishii H, Hyodo F, Samuni U, Krishna MC, Goldstein S, Mitchell JB. Reactive oxygen species mediate hepatotoxicity induced by the Hsp90 inhibitor geldanamycin and its analogs. Free Radical Biology and Medicine. 48(11):1559-63. 2010
  • Hyodo F, Matsumoto S, Hyodo E, Matsumoto A, Matsumoto K, Krishna MC. In vivo measurement of tissue oxygen using electron paramagnetic resonance spectroscopy with oxygen-sensitive paramagnetic particle, lithium phthalocyanine Methods in Molecular Biology. 610 23-39 2010
  • Hyodo F, Matsumoto, S, Devasahayam, N,Dharmaraj, C,Subramanian, S,Mitchell, JB and Krishna, MC. Pulsed EPR imaging of nitroxides in mice. Journal of Magnetic Resonance 197 181-185 2009
  • Hyodo F, Chandramouli, GV, Matsumoto, S, Matsumoto, K, Mitchell, JB, Krishna, MC and Munasinghe, JP. Estimation of tumor microvessel density by MRI using a blood pool contrast agent. International Journal of Oncology 35 797-804 2009
  • 兵藤文紀、内海英雄 生体磁気共鳴レドックスイメージング 薬剤学Vol 62 (2) p103-111 2009
  • Yasuda S, Ikuta K, Uwatoku T, Oi K, Abe K, Hyodo F, Yoshimitsu K, Sugimura K, Utsumi H, Katayama Y, Shimokawa H. In vivo magnetic resonance imaging of atherosclerotic lesions with a newly developed Evans blue-DTPA-gadolinium contrast medium in apolipoprotein-E-deficient mice. Journal of Vascular Research. 45(2) 123-8 2008
  • Matsumoto S, Hyodo F, Subramanian S, Devasahayam N, Munasinghe J, Hyodo E, Gadisetti C, Cook JA, Mitchell JB and Krishna MC. Low-field paramagnetic resonance imaging of tumor oxygenation and glycolytic activity in mice. Journal of Clinical Investigation 118 1965-1973 2008
  • Hyodo F, Soule BP, Matsumoto K, Matusmoto S, Cook JA, Hyodo E, Sowers AL, Krishna MC and Mitchell JB. Assessment of tissue redox status using metabolic responsive contrast agents and magnetic resonance imaging. Journal of Pharmacy and Pharmacology 60 1049-1060 2008
  • Hyodo F, Chuang, KH, Goloshevsky, AG,Sulima, A,Griffiths, GL,Mitchell, JB, Koretsky, AP and Krishna, MC. Brain redox imaging using blood-brain barrier-permeable nitroxide MRI contrast agent. Journal of Cerebral Blood Flow Metabolism 28 1165-1174 2008
  • Hyodo F, Murugesan, R, Matsumoto, K, Hyodo, E,Subramanian, S, Mitchell, JB and Krishna, MC. Monitoring redox-sensitive paramagnetic contrast agent by EPRI, OMRI and MRI. Journal of Magnetic Resonance 190 105-112 2008
  • Hyodo F, Subramanian, S, Devasahayam, N, Murugesan, R,Matsumoto, K, Mitchell, JB and Krishna, MC. Evaluation of sub-microsecond recovery resonators for in vivo electron paramagnetic resonance imaging. Journal of Magnetic Resonance 190 248-254 2008
  • Isenberg, JS, Maxhimer, JB, Hyodo F, Pendrak, ML,Ridnour, LA, DeGraff, WG, Tsokos, M, Wink, DA and Roberts, DD. Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury.    American Journal of Pathology 173 1100-1112 2008
  • Isenberg JS, Hyodo F, Ridnou LA, Shanno CS, Wink DA, Krishna MC and Robert, DD. Thrombospondin 1 and vasoactive agents indirectly alter tumor blood flow. Neoplasia 10 886-896 2008